Research Area / Interest
Dr. Kim’s research focuses on three main areas.
1. Biomarker Discovery:
She is actively engaged in biomarker discovery, aiming to identify diagnostic, prognostic and therapeutic markers through multi-omics data analyses of both tissue and liquid biopsy samples. Her research focuses not only on marker discovery but also on elucidating their underlying molecular mechanisms and functions. This includes the development of non-invasive biomarkers for disease monitoring and therapeutic response assessment.
2. Genomic and Epigenetic Regulation:
She investigates the regulatory mechanisms of gene expression in human diseases, with a particular emphasis on integrative analysis of DNA mutation, chromatin accessibility, histone modifications, and transcription factor networks. Her work seeks to uncover how these regulatory layers contribute to disease onset and progression.
3. Precision Medicine and Therapeutic Stratification:
She leads studies in precision medicine, classifying molecular subtypes of human disease and predicting drug responsiveness using integrated genomic, transcriptomic, and clinical datasets. Her group applies advanced computational pipelines, machine learning models, and statistical frameworks combined with in vitro/in vivo functional validation.
Recently, she has focused on identifying non-coding mutations as biomarkers using AI-based methods and experimental approaches. She also develops customized pipelines to discover novel neo-genes involved in human disease. Through these efforts, Dr. Kim aims to contribute to the development of personalized and targeted therapeutic strategies in human disease.
